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Alterations in Promoter Methylation Status of Tumor Suppressor HIC1 , SFRP2 , and DAPK1 Genes in Prostate Carcinomas

✍ Scribed by Kilinc, Devran; Ozdemir, Oztürk; Ozdemir, Semra; Korgali, Esat; Koksal, Binnur; Uslu, Atilla; Gultekin, Yener E.

Book ID: 125484382
Publisher: Mary Ann Liebert
Year: 2012
Tongue: English
Weight: 246 KB
Volume: 31
Category: Article
ISSN: 1044-5498
DOI: 10.1089/dna.2011.1431

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## Abstract Tumor suppressor genes (TSGs) are sometimes inactivated by transcriptional silencing through promoter hypermethylation. To identify novel methylated TSGs in melanoma, we carried out global mRNA expression profiling on a panel of 12 melanoma cell lines treated with a combination of 5‐Aza