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Alterations in myocardial energy metabolism induced by the anti-cancer drug doxorubicin

โœ Scribed by Malgorzata Tokarska-Schlattner; Theo Wallimann; Uwe Schlattner


Book ID
116391568
Publisher
Elsevier Science
Year
2006
Tongue
French
Weight
258 KB
Volume
329
Category
Article
ISSN
1631-0691

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Large differences in induced cellular toxicity were observed in the presence or absence of a rat liver micro-soma1 metabolizing system (S-9) during drug testing in the mouse lymphoma assay. After studying the fate of three drugs in this test system, several mechanisms were demonstrated whereby S-9 r