𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Alterations in Gene Expression in Response to Compression of Nucleus Pulposus Cells

✍ Scribed by Gwendolyn Sowa; J. Paulo Coelho; Kevin Bell; Patrick Smolinski; Rebecca Studer; Nam Vo; James Kang

Book ID
119371638
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
106 KB
Volume
9
Category
Article
ISSN
1529-9430

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Environmental regulation of notochordal
Environmental regulation of notochordal gene expression in nucleus pulposus cells
✍ Anshu Rastogi; Pratiksha Thakore; Aileen Leung; Magda Benavides; Monica Machado; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 336 KB

## Abstract Cells of the nucleus pulposus (NP) in the intervertebral disc are derived directly from the embryonic notochord. In humans, a shift in NP cell population coincides with the beginning of age‐related changes in the extracellular matrix that can lead to spinal disorders. To begin identifyi

Prolonged down regulation of specific ge
Prolonged down regulation of specific gene expression in nucleus pulposus cell mediated by RNA interference in vitro
✍ Kenichiro Kakutani; Kotaro Nishida; Koki Uno; Toru Takada; Takatoshi Shimomura; πŸ“‚ Article πŸ“… 2006 πŸ› Elsevier Science 🌐 English βš– 302 KB

## Abstract To investigate the efficacies and the longevity of RNA interference in nucleus pulposus cells from rat and human, two reporter luciferase plasmids (__Firefly__ and __Renilla__) were used. These plasmids were cotransfected with siRNA targeting __Firefly__ luciferase to the nucleus pulpos

Alterations of ADAMTSs and TIMP-3 in hum
Alterations of ADAMTSs and TIMP-3 in human nucleus pulposus cells subjected to compressive load: Implications in the pathogenesis of human intervertebral disc degeneration
✍ Ming Huang; Hai-Qiang Wang; Qiang Zhang; Xiao-Dong Yan; Meng Hao; Zhuo-Jing Luo πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 English βš– 266 KB

## Abstract Intervertebral disc degeneration (IDD) pertains to the loss of extracellular matrix (ECM), particularly the early loss of aggrecan, the turnover of which is regulated by ADAMTSs. Amongst the etiological factors of IDD, mechanical stress plays an important role in the physiological and p