ALTERATIONS IN EPIDERMAL GROWTH KINETICS INDUCED BY COAL TAR OINTMENT AND METHOTREXATE.

Altered expression of epidermal growth f

Altered expression of epidermal growth factor receptor ligands in tumor promoter–treated mouse epidermis and in primary mouse skin tumors induced by an initiation-promotion protocol

✍ Kaoru Kiguchi; Linda Beltrán; Tim Rupp; John DiGiovanni 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 734 KB

Multiple epidermal growth factor receptor (EGFr) ligands have been identified, including transforming growth factor α (TGFα), heparin-binding epidermal growth factor (HB-EGF), amphiregulin (AR), and betacellulin (BTC). Previous work from our laboratory demonstrated that TGFα mRNA and protein are upr