Alterations in components of the ubiquitin-protein ligase system following maturation of reticulocytes to erythrocytes
โ Scribed by Osnat Raviv; Hannah Heller; Avram Hershko
- Book ID
- 115760615
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 985 KB
- Volume
- 145
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract How the metabolic defect of pyruvate kinase deficiency (PK(โ)) accelerates red blood cell (RBC) destruction is not established, but may be related to RBC membrane abnormalities associated with altered cellular metabolism. Furthermore, it has been shown that PK(โ) reticulocytes are espec
## Abstract ## BACKGROUND Low levels of p27^Kip1^ are associated with high aggressiveness and poor prognosis in various malignancies, including colorectal carcinoma. The authors showed that S phase kinase protein 2 (Skp2), the specific ubiquitin ligase subunit that targets p27^Kip1^ for degradatio