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Alterations in canine vertebral bone turnover, microdamage accumulation, and biomechanical properties following 1-year treatment with clinical treatment doses of risedronate or alendronate

โœ Scribed by Matthew R. Allen; Ken Iwata; Roger Phipps; David B. Burr


Book ID
116319724
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
293 KB
Volume
39
Category
Article
ISSN
8756-3282

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Alterations in canine vertebral bone tur
โœ Matthew R. Allen; Ken Iwata; Roger Phipps; David B. Burr ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 293 KB

One year of treatment with bisphosphonates at 5ร— the dose used for post-menopausal osteoporosis significantly increases failure load and microdamage, and decreases toughness at multiple skeletal sites in intact female beagles. The goal of this study was to determine if similar changes occur with dos