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Alteration to the SWI/SNF complex in human cancers

✍ Scribed by Vanessa S. Gordon; Colin Rogers; David Reisman

Book ID
107616010
Publisher
PAGEPress Publications
Year
2010
Tongue
English
Weight
280 KB
Volume
4
Category
Article
ISSN
1970-5557

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## Abstract The acute myeloid leukemia 1 (AML1, RUNX1) transcription factor is a key regulator of hematopoietic differentiation that forms multi‐protein complexes with co‐regulatory proteins. These complexes are assembled at target gene promoters in nuclear microenvironments to mediate phenotypic g