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Alteration of NRSF expression exacerbating 1-methyl-4-phenyl-pyridinium ion-induced cell death of SH-SY5Y cells

✍ Scribed by Mei Yu; Lei Cai; Min Liang; Yalin Huang; Hui Gao; Shiduo Lu; Jian Fei; Fang Huang


Book ID
116776150
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
674 KB
Volume
65
Category
Article
ISSN
0168-0102

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Growth arrest DNA damage-inducible 153 (GADD153) expression was increased in 1-methyl-4-phenyl-pyridinium (MPP(+))-treated human SH-SY5Y neuroblastoma cells as determined by gene microarray analysis. GADD153 expression increased after 24 hr of MPP(+) (1 mM) exposure and preceded activation of caspas