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Alteration of Intracellular Structure and Function of Glyceraldehyde-3-Phosphate Dehydrogenase: A Common Phenotype of Neurodegenerative Disorders?

✍ Scribed by Jennifer L. Mazzola; Michael A. Sirover


Book ID
117330026
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
120 KB
Volume
23
Category
Article
ISSN
0161-813X

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Subcellular alteration of glyceraldehyde
✍ Jennifer L. Mazzola; Michael A. Sirover πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 179 KB

## Abstract The regulation of glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) has been implicated both in age‐related neurodegenerative disease and in apoptosis. Previous in vitro studies suggest an interaction between GAPDH and the β‐amyloid precursor protein (β‐APP), a protein directly involved