Alteration of immunoregulatory mechanisms during cytomegalovirus mononucleosis: Effect of in vitro culture on lymphocyte blastogenesis to viral antigens

Effect of human serum anti-htlv antibodi

Effect of human serum anti-htlv antibodies on viral antigen induction in In vitro cultured peripheral lymphocytes from adult T-CELL leukemia patients and healthy virus carriers

✍ Tadafumi Tochikura; Masato Iwahashi; Tadashi Matsumoto; Yoshio Koyanagi; Yorio H 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 618 KB

## Abstract Leukemic cells of adult T‐cell leukemia (ATL) patients contain human T‐cell leukemia virus type I (HTLV‐I) genomes. However, viral antigens (HTLV‐A) are not usually expressed __in vivo__. It has been shown that HTLV‐I antigens are spontaneously induced after culture of peripheral blood