Metabolic Engineering of Escherichia col
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Susana J. BerrΔ±́os-Rivera; George N. Bennett; Ka-Yiu San
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Article
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2002
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Elsevier Science
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English
β 200 KB
Metabolic engineering studies have generally focused on manipulating enzyme levels through either the amplification, addition, or deletion of a particular pathway. However, with cofactor-dependent production systems, once the enzyme levels are no longer limiting, cofactor availability and the ratio