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Alteration of hydrogen metabolism ofldh-deletedEnterobacter aerogenesby overexpression of NAD(+)-dependent formate dehydrogenase

✍ Scribed by Yuan Lu; Hongxin Zhao; Chong Zhang; Qiheng Lai; Xi Wu; Xin-Hui Xing


Book ID
105952339
Publisher
Springer
Year
2009
Tongue
English
Weight
221 KB
Volume
86
Category
Article
ISSN
1432-0614

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Metabolic engineering studies have generally focused on manipulating enzyme levels through either the amplification, addition, or deletion of a particular pathway. However, with cofactor-dependent production systems, once the enzyme levels are no longer limiting, cofactor availability and the ratio