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Alteration of HGF and TSP-1 expression in ovarian carcinoma associated with clinical features

โœ Scribed by Wei Wei; Beihua Kong; Xun Qu


Book ID
109007724
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
805 KB
Volume
38
Category
Article
ISSN
1341-8076

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Altered expression of cyclin D1 and CDK4
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We analyzed the expression and amplification of cyclin D1 and CDK4 genes in ovarian carcinomas. Northern blot analysis revealed overexpression of cyclin D1 in 12 of 65 (18%) ovarian carcinomas while CDK4 was overexpressed in 7 of 48 cases (14%). None of the tumors showed amplification of any of the