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Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment

✍ Scribed by Frédéric Calon; Marc Morissette; Othman Ghribi; Martin Goulet; Richard Grondin; Pierre J Blanchet; Paul J Bédard; Thérèse DiPaolo


Book ID
117448879
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
217 KB
Volume
26
Category
Article
ISSN
0278-5846

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✍ P. J. Blanchet; R. Grondin; Dr. P. J. Bédard 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 563 KB

## Abstract The motor effects of the short‐acting, full D~1~ agonist SKF 82958 were studied in three drug‐naive, 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine‐lesioned, parkinsonian monkeys treated for 4 weeks. D~1~ receptor stimulation with SKF 82958 effectively relieved parkinsonism but induced