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Alteration of 8-hydroxyguanosine concentrations in the cerebrospinal fluid and serum from patients with Parkinson's disease

✍ Scribed by Takashi Abe; Chiaki Isobe; Takahiko Murata; Chigumi Sato; Hideo Tohgi

Book ID
117473413
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
82 KB
Volume
336
Category
Article
ISSN
0304-3940

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Remarkable increase in the concentration
Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease
✍ Takashi Abe; Hideo Tohgi; Chiaki Isobe; Takahiko Murata; Chigumi Sato πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 76 KB πŸ‘ 1 views

## Abstract To investigate the possible role of oxidative RNA damage in the pathogenesis of Alzheimer's disease (AD), the concentrations of the oxidative stress marker 8‐hydroxyguanosine (8‐OHG) were measured in the cerebrospinal fluid (CSF) and the serum of patients with AD and control subjects. T