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Alteration in Indinavir Clearance During Interleukin-2 Infusions in Patients Infected with the Human Immunodeficiency Virus

✍ Scribed by Stephen C. Piscitelli; Susan Vogel; William D. Figg; Sangeeta Raje; Alan Forrest; Julia A. Metcalf; Michael Baseler; Judith Falloon


Book ID
112113762
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
447 KB
Volume
18
Category
Article
ISSN
0277-0008

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To characterize the immunological effects of intermittent IL-2 therapy, which leads to selective increases in CD4 + T lymphocytes in HIV-infected patients, 11 patients underwent extensive immunological evaluation. While IL-2 induced changes in both CD4 + and CD8 + cell number acutely, only CD4 + cel