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Alprazolam in the elderly: pharmacokinetics and pharmacodynamics during multiple dosing

✍ Scribed by Patricia D. Kroboth; James W. McAuley; Randall B. Smith


Publisher
Springer
Year
1990
Tongue
English
Weight
906 KB
Volume
100
Category
Article
ISSN
0033-3158

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Pharmacokinetics and pharmacodynamics of
✍ Oberbauer, Rainer; Krivanek, Peter; Turnheim, Klaus πŸ“‚ Article πŸ“… 1995 πŸ› Nature Publishing Group 🌐 English βš– 896 KB

In a cross-sectional study of the pharmacokinetics and pharmacodynamics of peroral and intravenous bumetanide (0.5 mg, single dose), total and renal clearance of the diuretic was si~ni6cantly lower in elderly persons than in young adults, resulting in higher bumetanide plasma levels in the aged. Non