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Alpha tocopherol quinone (αTQ): A potent inhibitor of platelet function

✍ Scribed by Gundu H.R. Rao; Chadwick A. Cox; Jonathan M. Gerrard; James G. White


Book ID
118385703
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
226 KB
Volume
20
Category
Article
ISSN
0163-7827

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Synthetic vitamin E, dl-alpha-tocopherol, added to a human erythroleukemia HEL and a megakaryoblastic leukemia, Meg-01, cell culture produced potent dose-dependent inhibition of phorbol ester-induced adhesion and of the morphologic changes accompanying it. The inhibition was reversible by withdrawal