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Alpha-Synuclein Binds to the Inner Membrane of Mitochondria in an α-Helical Conformation

✍ Scribed by Robotta, Marta; Gerding, Hanne R.; Vogel, Antonia; Hauser, Karin; Schildknecht, Stefan; Karreman, Christiaan; Leist, Marcel; Subramaniam, Vinod; Drescher, Malte

Book ID
126668770
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
925 KB
Volume
15
Category
Article
ISSN
1439-4227

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## Abstract The putative function of the Parkinson's disease‐related protein α‐Synuclein (__α__S) is thought to involve membrane binding. Therefore, the interaction of αS with membranes composed of zwitterionic (POPC) and anionic (POPG) lipids was investigated through the mobility of spin labels at