Human telomerase reverse transcriptase, hTERT, has been identified as the catalytic enzyme required for telomere elongation. hTERT is expressed in most tumor cells but seldom expressed in most human adult cells. It has been reported that 80% to 90% of hepatocellular carcinomas (HCCs) express hTERT,
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Alpha-fetoprotein and human telomerase reverse transcriptase mRNA levels in peripheral blood of patients with hepatocellular carcinoma
โ Scribed by Sun-Young Kong; Joong-Won Park; Jin Oak Kim; Nam Oak Lee; Jung An Lee; Kyung Woo Park; Eun Kyung Hong; Chang-Min Kim
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 312 KB
- Volume
- 135
- Category
- Article
- ISSN
- 1432-1335
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## Abstract ## BACKGROUND The objectives of this study were to evaluate the diagnostic and prognostic relevance of human telomerase reverse transcriptase (hTERT) detected in situ in patients with nonsmall cell lung carcinoma (NSCLC) and to investigate the possible correlations between hTERT mRNA i
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