Alpha-chloralose is a suitable anesthetic for chronic focal cerebral ischemia studies in the rat: A comparative study
β Scribed by Janos Luckl; Jeffrey Keating; Joel H. Greenberg
- Book ID
- 113503217
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 513 KB
- Volume
- 1191
- Category
- Article
- ISSN
- 0006-8993
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Combined NMR imaging and spectroscopy have been applied to mouse brain during focal cerebral ischemia. The present study evaluated the feasibility of NMR measurements on mice in order to fine-tune the sequences and experimental setup for systematic investigations on stroke including future studies o
## Abstract Using microdialysis in CA1 of the rat hippocampus, we studied the effect of transient cerebral ischemia on in vivo uptake and on extracellular levels of glutamate during, and at different time points after ischemia. ^3^HβDβaspartate (test substance), and ^14^Cβmannitol (reference substa