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Alpha 1,3-fucosyltransferase-VII regulates the signaling molecules of the insulin receptor pathway

✍ Scribed by Qiu-yan Wang; Ying Zhang; Hai-jiao Chen; Zong-hou Shen; Hui-li Chen

Book ID
111311764
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
927 KB
Volume
274
Category
Article
ISSN
1432-1327

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Ξ±1,3 fucosyltransferase-VII up-regulates
Ξ±1,3 fucosyltransferase-VII up-regulates the mRNA of Ξ±5 integrin and its biological function
✍ Qiu-yan Wang; Ying Zhang; Zong-hou Shen; Hui-li Chen πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 263 KB

## Abstract After transfection of Ξ±1,3fucosyltransferase (FucT)‐VII cDNA into H7721 human hepatocarcinoma cells, the expression of Ξ±5, but not Ξ²1 integrin was significantly up‐regulated. This was evidenced by the increase of Ξ±5 integrin on cell surface as well as the increase of Ξ±5 mRNA and protein