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ALPHA-1-ANTITRYPSIN AND RHEUMATOID ARTHRITIS

✍ Scribed by Walsh, L.; Mcconkey, B.

Book ID
123284331
Publisher
The Lancet
Year
1977
Tongue
English
Weight
269 KB
Volume
310
Category
Article
ISSN
0140-6736

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Alpha,-antitrypsin (a-AT) is a protease inhibitor system consisting of more than 30 phenotypic alleles, which can be differentiated by polyacrylamide gel-isoelectric focusing. The most common alleles are designated PiM, Pis, and PiZ. The phenotype MM is found in about 90% of the U.S. white populatio