PACAP provides colonic protection agains
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Yasu-Taka Azuma; Kiyomi Hagi; Norihito Shintani; Mitsuru Kuwamura; Hidemitsu Nak
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Article
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2008
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John Wiley and Sons
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English
⚖ 447 KB
## Abstract Pituitary adenylate cyclase‐activating polypeptide (PACAP) plays a crucial role in immunity and inflammation. Our aim was to obtain insight in the role of PACAP in experimental colitis in mice and thus its possible role in inflammatory bowel disease. PACAP‐deficient (__PACAP__^−/−^) mic