Identification and characterization of o
β
Mukesh K. Mahajan; Vinita Uttamsingh; Liang-Shang Gan; Barbara Leduc; David A. W
π
Article
π
2011
π
John Wiley and Sons
π
English
β 386 KB
The incubation of oxymetazoline, a nonprescription nasal decongestant, with human liver microsomes (HLMs) supplemented with uridine-5-diphosphoglucuronic acid (UDPGA) generated glucuronide metabolite as observed by LC/MS/MS. The uridine glucuronosyltransferases (UGTs) responsible for the O-glucuroni