Allylic substitution in water catalyzed by amphiphilic resin-supported palladium-phosphine complexes

✍ Scribed by Hiroshi Danjo; Daiki Tanaka; Tamio Hayashi; Yasuhiro Uozumi

• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 732 KB
• Volume: 55
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(99)00883-2

✦ Synopsis

New amphiphilic resin-supported triarylphosphines PEP (1) were designed and prepared on polyethylene glycol-polystyrene graft copolymer (PEG-PS). Palladium complexes of 1, Pd(PEP)2 (4) and Pd(PEP) (5), catalyzed allylic alkylation of 3-acetoxy-1,3-diphenyl-1-propene (6) and cinnamyl acetate (7) with various nucleophiles including 1,3-dicarbonyl compounds, amino acids, sodium azide, and sodium sulfinate, to give quantitative yields of corresponding allylic substituted products in water.