On the allyl protection of the imidazole
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A Malanda Kimbonguila; S Boucida; F Guibรฉ; A Loffet
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Article
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1997
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Elsevier Science
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French
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The regiospecific synthesis of the N(~)-allyl and the N(r)-allyl derivatives of N(otFtertbutoxycarbonyl-histidine is described. The DCC-mediated coupling of N(~)-tert-butoxycarbonyl-N(~)allyl-(L)-histidine with (L)-prolinamide, used as a test reaction to probe the extent of racemization duriug coupl