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Allosteric Regulation of the Epidermal Growth Factor Receptor

✍ Scribed by Bagchi, Atrish; Bessman, Nicholas J.; Wu, Neo Z.; Raines, Lily; Kan, Zhongyuan; Hu, Wenbing; Englander, S. Walter; Leahy, Daniel J.; Lemmon, Mark A.; Ferguson, Kathryn M.

Book ID
122279758
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
45 KB
Volume
106
Category
Article
ISSN
0006-3495

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Regulation of the epidermal growth facto
Regulation of the epidermal growth factor receptor by phosphorylation
✍ Paul J. Bertics; Wolfgang Weber; Claude Cochet; Gordon N. Gill πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 840 KB

The receptor for epidermal growth factor (EGF) is a glycosylated transmembrane phosphoprotein that exhibits EGF-stimulable protein tyrosine kinase activity. On EGF stimulation, the receptor undergoes a self-phosphorylation reaction at tyrosine residues located primarily in the extreme carboxyl-termi