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Allosteric regulation of aspartate transcarbamoylase. Changes in the sedimentation coefficient promoted by the bisubstrate analog N-(phosphonacetyl)-L-aspartate

โœ Scribed by Howlett, G. J.; Schachman, H. K.


Book ID
127140213
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
870 KB
Volume
16
Category
Article
ISSN
0006-2960

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A high-resolution structure of Escherichia coli aspartate transcarbamoylase has been determined to 2.1 ร…; resolution in the presence of the bisubstrate analog N-phosphonacetyl-L-aspartate (PALA). The structure was refined to a free R-factor of 23.4% and a working R-factor of 20.3%. The PALA molecule