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Allosteric modulation of the mouse kir6.2 channel by intracellular H+ and ATP

✍ Scribed by Jianping Wu; Ningren Cui; Hailan Piao; Ying Wang; Haoxing Xu; Jinzhe Mao; Chun Jiang

Book ID
110111961
Publisher
Cambridge University Press
Year
2002
Tongue
English
Weight
264 KB
Volume
543
Category
Article
ISSN
0022-3751

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πŸ“œ SIMILAR VOLUMES

Critical protein domains and amino acid
Critical protein domains and amino acid residues for gating the KIR6.2 channel by intracellular ATP
✍ Jianping Wu; Hailan Piao; Asheebo Rojas; Runping Wang; Ying Wang; Ningren Cui; Y πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 220 KB

## Abstract K~ATP~ channels couple intermediary metabolism to cellular excitability. Such a property relies on the inherent ATP‐sensing mechanism known to be located in the Kir6 subunit. However, the molecular basis for the ATP sensitivity remains unclear. Here we showed evidence for protein domain