𝔖 Bobbio Scriptorium
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Allosteric Binding Properties of a Monoclonal Antibody and Its Fab Fragment †

✍ Scribed by Blake, Robert C.; Delehanty, James B.; Khosraviani, Mehraban; Yu, Haini; Jones, R. Mark; Blake, Diane A.

Book ID
121882781
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
163 KB
Volume
42
Category
Article
ISSN
0006-2960

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## Abstract An antigastric cancer monoclonal antibody, 3H11 and its Fab fragment, were labelled with a‐emitter ^211^At using p‐(^211^At)‐astatobenzoic acid (pAtBA) intermediate, in the yields of more than 30%. The astatinated antibodies were stable in vitro, and had specific immunoreactivity to hum