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Allogeneic hematopoietic cell transplantation for paroxysmal nocturnal hemoglobinuria

โœ Scribed by Jae-Lyun Lee; Je-Hwan Lee; Jung-Hee Lee; Seong-Jun Choi; Shin Kim; Miee Seol; Young-Shin Lee; Hyun-Sook Chi; Chan-Jeoung Park; Woo-Kun Kim; Jung-Shin Lee; Kyoo-Hyung Lee


Book ID
114423256
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
93 KB
Volume
71
Category
Article
ISSN
0902-4441

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Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal stem-cell disorder in which blood cells lack complement inhibiting membrane proteins, and become susceptible to complement-mediated injury, leading to chronic intravascular hemolysis and pancytopenia. Glucocorticoids have been a mainstay of