Allogeneic Bone Marrow Transplantation in First Remission for Children with Ultra-high-risk Features of Acute Lymphoblastic Leukemia: A Children’s Oncology Group Study Report
✍ Scribed by Prakash Satwani; Harland Sather; Fevzi Ozkaynak; Nyla A. Heerema; Kirk R. Schultz; Jean Sanders; John Kersey; Virginia Davenport; Michael Trigg; Mitchell S. Cairo
- Book ID
- 116279129
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 168 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1083-8791
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## Abstract ## Background The prognosis of Philadelphia chromosome‐positive acute lymphoblastic leukemia (Ph^+^ ALL) is generally poor and reports from large studies are scarce. We evaluated the efficacy of allogeneic bone marrow transplantation (allo‐BMT) for children with this type of leukemia.
Background. Maintenance of second remission of childhood acute lymphoblastic leukemia (ALL) with intensive chemotherapy is often unsuccessful. The major cause of treatment failure is relapse. Materials and Methods. Of 96 children with ALL who relapsed in the marrow while on or within 1 year of comp