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Alloantibody from a patient with severe von Willebrand disease inhibits von Willebrand factor-FVIII interaction

✍ Scribed by J. Batlle; E. Lourés; P. Vila; M. C. Hernández; J. A. Méndez; J. Torea; E. Rendal; M. J. Couselo; A. Filgueira; M. F. López Fernández


Publisher
Springer
Year
1997
Tongue
English
Weight
185 KB
Volume
75
Category
Article
ISSN
0939-5555

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A patient with type 2N ("Normandy" variant) von Willebrands disease is described. Her von Willebrand factor level was borderline low, while her factor Vlll was markedly decreased to 7%. Her plasma von Wlliebrand factor demonstrated a decreased ability to complex with factor Vlll In vitro, binding le