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Allergy to lipocalins: a consequence of misguided T-cell recognition of self and nonself?

✍ Scribed by Tuomas Virtanen; Thomas Zeiler; Jaakko Rautiainen; Rauno Mäntyjärvi


Book ID
104299149
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
145 KB
Volume
20
Category
Article
ISSN
0167-5699

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✍ Rong Hwa Lin; Brigitta Stockinger 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 691 KB

In this study we investigated the basis for immunity or tolerance to a mouse serum protein, the fifth component of complement (C5). In CS-deficient mice this protein is absent from serum and therefore they are not tolerized. Immunization of CS-deficient mice with C5-sufficient serum generates CD4' T