Allergic Contact Dermatitis: The Molecular Basis

✍ Scribed by David A. Basketter, An Goossens, Ann-Therése Karlberg (auth.), Dr. Jean-Pierre Lepoittevin D.Sc., David A. Basketter, Dr. An Goossens Ph.D., Dr. Ann-Therése Karlberg Ph.D. (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 1998
• Tongue: English
• Leaves: 193
• Edition: 1
• Category: Library

✦ Synopsis

Allergic Contact Dermatitis presents all up-to-date chemical and physio-chemical concepts for the study and understanding of allergic contact dermatitis (ACD). The book covers all aspects of ACD - skin penetration and metabolism, identification of sensitizers and hapten-protein interaction, including new concepts of increasing importance such as molecular recognition and quantitative structure-activity relationships. In addition, comprehensive references are provided, making this the most complete available text-book for dermatologists.
Allergic Contact Dermatitis reaches an equilibrium between fundamental concepts and clinical applications and thus presents an essential guideline to dermatologists, allergologists, biochemists and toxicologists.

✦ Table of Contents

Front Matter....Pages I-X
Introduction....Pages 1-3
Immunological Aspects....Pages 4-18
Chemical Basis....Pages 19-42
Isolation and Identification of Contact Allergens....Pages 43-67
Skin Metabolism....Pages 68-80
Hapten-Protein Interactions....Pages 81-111
Molecular Basis for the Recognition of Haptens by T Lymphocytes....Pages 112-128
Structure—Activity Relationships for Contact Hypersensitivity....Pages 129-154
The Practical Approach....Pages 155-179
Back Matter....Pages 181-186

✦ Subjects

Dermatology; Allergology