Paraβtertiaryβbutylcatechol (PTBC) is a rare but potent contact allergen. This is a report of occupational allergic contact dermatitis to PTBC in a resin operator.
Allergic contact dermatitis due to benzalkonium chloride in plaster of Paris
β Scribed by Deanna A Wong; Alan B Watson
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 121 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0004-8380
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β¦ Synopsis
SUMMARY
Plaster of Paris (POP) bandages are extensively used for splinting and casting injured or surgically repaired body parts. Allergic contact dermatitis caused by POP has been reported only rarely in the medical literature. An 81βyearβold woman developed multiple large, tense, haemorrhagic bullae on the palm, and an acute vesicular eczematous eruption on the forearm, after the application of a POP splint. Subsequent patch testing revealed positive reactions to both the POP bandage used and to benzalkonium chloride, a component of the POP formulation. Patch tests to two other POP products without benzalkonium chloride were negative. These results confirm those of previous studies which have implicated the quaternary ammonium compound benzalkonium chloride as the allergen responsible for POPβinduced allergic contact dermatitis.
π SIMILAR VOLUMES
The use of a lymphocyte transformation test (LTT) to provide evidence of allergic contact dermatitis was investigated. The haptens studied were alantolactone and isoalantolactone, two moderate allergens from Inula helenium L., a decorative and medicinal plant. Only alantolactone showed a significant
## Abstract Using an __in vitro__ assay for CD80 promoter activity, the transcriptional response of primary cultured human keratinocytes from different donors in response to allergens and irritants was studied. The CD80 promoter activity was increased reproducibly after exposure to certain chemical