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Allergenic sesquiterpene lactones from Eupatorium cannabinum L. and Kaunia rufescens (Lund ex de Candolle)†

✍ Scribed by Gerhard Rücker; Eloir P. Schenkel; Detlef Manns; Ralf Mayer; B. M. Hausen; Klemens Heiden


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
70 KB
Volume
5
Category
Article
ISSN
1056-9014

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✦ Synopsis


From Eupatorium cannabinum L., a hitherto unknown alpha-methylene-gamma-butyrolactone, 3 beta-peroxyeucannabinolide, was isolated. This compound and eupatoriopicrin from the same plant showed a weak sensitizing capacity in guinea pigs. 2-oxoludartin and dehydroleucodin, isolated from Kaunia rufescens (syn. Eupatorium rufescens), were strong sensitizers in the same sensitizarian procedure.