Allelotype of human breast carcinoma: Present status and deletion-mapping on chromosomes 3p, 6, and 18q.
โ Scribed by P. Devilee; M. van Vliet; P. van Sloun; A. Bardoel; N. Kuipers-Dijkshoorn; C.J. Cornelisse
- Book ID
- 119105150
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 53 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0165-4608
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Loss of heterozygosity (LOH) on 3p is frequent in human renal cell carcinomas, lung cancers, and breast cancers. To define the region(s) on 3p that harbor presumptive tumor suppressor gene(s) for breast cancer, we examined 196 primary breast tumors for their patterns of LOH at 22 microsatellite mark
To identify common regions of deletion in human testicular germ cell tumors (TGCTs), we have screened tumors from 33 patients for loss of heterozygosity (LOH) using Southern blot analysis with 39 polymorphic markers covering 21 chromosome arms. Losses in more than 2 tumors and occurring at a frequen