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Allelic Variation in the Serotonin Transporter Promoter Affects Onset of Paroxetine Treatment Response in Late-Life Depression

✍ Scribed by Bruce G Pollock; Robert E Ferrell; Benoit H Mulsant; Sati Mazumdar; Mark Miller; Robert A Sweet; Stephanie Davis; Margaret A Kirshner; Patricia R Houck; Jacqueline A Stack; Charles F Reynolds III; David J Kupfer


Book ID
114280673
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
252 KB
Volume
23
Category
Article
ISSN
1470-634X

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## Abstract In the present study, we investigated the relationship between the serotonin transporter gene linked polymorphic regions (5‐HTTLPR) or plasma paroxetine levels and clinical response to paroxetine in depressed patients. Sixty patients who met the DSM‐IV criteria for major depressive diso