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Allelic loss on chromosome band 18p11.3 occurs early and reveals heterogeneity in breast cancer progression

✍ Scribed by Kanokwan Kittiniyom, Karen M Gorse, Fabienne Dalbegue, Jack H Lichy…

Book ID
120700770
Publisher
BioMed Central
Year
2001
Tongue
English
Weight
1011 KB
Volume
3
Category
Article
ISSN
1465-5411

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✍ Heba M. S. Ismail; Amina M. Medhat; Amr M. Karim; Nadia I. Zakhary 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 761 KB

## Abstract The fragile histidine triad gene (FHIT) is a candidate tumor suppressor gene at chromosome 3p14.2. Deletions in FHIT gene were reported in different types of cancer including breast cancer. In this study, we investigated the loss of heterozygosity (LOH) incidence that target FHIT genomi