Allelic loss on chromosome 22 correlates with histopathological predictors of recurrence of meningiomas
✍ Scribed by Marc Sanson; Stéphane Richard; Olivier Delattre; Marc Poliwka; Jacqueline Mikol; Jacques Philippon; Gilles Thomas
- Book ID
- 102277077
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- French
- Weight
- 473 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0020-7136
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An extended analysis for loss of heterozygosity (LOH) on eight chromosomes was conducted in a series of 82 Wilms tumors. Observed rates of allele loss were: 9.5% (1p), 5% (4q), 6% (6p), 3% (7p), 9.8% (11q), 28% (11p15), 13.4% (16q), 8.8% (18p), and 13.8% (22q). Known regions of frequent allele loss
## BACKGROUND. Alterations in chromosome 1 are common in human malignancies. The frequency of loss of heterozygosity (LOH) on chromosome 1 in cervical carcinoma and its clinical significance are not clearly understood.