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Allelic loss of susceptibility loci and the occurrence of BRAF and RAS mutations in patients with familial non-medullary thyroid cancer

✍ Scribed by Kuk Young Na; Ra Mi Kim; Eun-Mi Song; Ji Hyun Lee; Jandee Lee; Euy-Young Soh

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
263 KB
Volume
105
Category
Article
ISSN
0022-4790

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## Abstract The __BRCA1__ and __BRCA2__ genes are responsible for a high proportion of familial breast cancer; germline mutations in these genes confer a lifetime risk of about 70% for developing breast cancer. Most of the described deleterious mutations are small deletions or insertions that origi