To evaluate the role of chromosome 13 deletions in oral squamous cell carcinoma (SCC) progression and to define the precise localization of putative tumor suppressor genes, we studied tumors from 34 unrelated patients with oral SCC by the polymerase chain reaction (PCR)-loss of heterozygosity (LOH)
โฆ LIBER โฆ
Allelic loss in human intrahepatic cholangiocarcinoma: Correlation between chromosome 8p22 and tumor progression
โ Scribed by Jun Kawaki; Masaru Miyazaki; Hiroshi Ito; Koji Nakagawa; Hiroaki Shimizu; Hiroyuki Yoshidome; Katsuhiro Uzawa; Hideki Tanzawa; Nobuyuki Nakajima
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 100 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0020-7136
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NM23 is a protein associated with tumor progression, expressed in all tissues and in human tumors. Reduced expression of NM23.H1 is related to high incidence of lymph node and distant metastasis or to poor prognosis of the patient in several human malignant tumors. In this study we analyze NM23 expr