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Allelic imbalance at chromosome 1q21 in Wilms tumor

✍ Scribed by Megan H. Law; Elizabeth Algar; Melissa Little

Book ID: 114136179
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 612 KB
Volume: 97
Category: Article
ISSN: 0165-4608
DOI: 10.1016/s0165-4608(96)00342-1

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An extended analysis for loss of heterozygosity (LOH) on eight chromosomes was conducted in a series of 82 Wilms tumors. Observed rates of allele loss were: 9.5% (1p), 5% (4q), 6% (6p), 3% (7p), 9.8% (11q), 28% (11p15), 13.4% (16q), 8.8% (18p), and 13.8% (22q). Known regions of frequent allele loss