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Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium

✍ Scribed by Thomas Sander; Helmut Harms; Jan Podschus; Ulrich Finckh; Bernd Nickel; Arndt Rolfs; Hans Rommelspacher; Lutz G. Schmidt

Book ID: 118065907
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 532 KB
Volume: 41
Category: Article
ISSN: 0006-3223
DOI: 10.1016/s0006-3223(96)00044-3

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## Abstract The presynaptic dopamine transporter in nigral dopaminergic neurons confers susceptibility to the cytotoxic effects of the neurotoxic metabolite of 1‐methy1‐4‐phenyl‐1,2,3,6‐tetrahydropyridine. Polymorphisms in the dopamine transporter might influence the susceptibility to such toxins.