Class I major histocompatibility complex (MHC) molecules interact with a diverse array of self and foreign peptides. Displayed on the cell surface, the class I/peptide complex provides an extracellular indication of the intracellular milieu. We have characterized the Lewis rat Vb8.21 T cell hybridom
✦ LIBER ✦
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
✍ Scribed by Falk, Kirsten; Rötzschke, Olaf; Stevanovié, Stefan; Jung, Günther; Rammensee, Hans-Georg
- Book ID
- 109777072
- Publisher
- Nature Publishing Group
- Year
- 1991
- Tongue
- English
- Weight
- 671 KB
- Volume
- 351
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/351290a0
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Class I major histocompatibility complex (MHC) molecules interact with a diverse array of self and foreign peptides, displaying them on the cell surface and providing an extracellular indication of intracel-M a r invasion. The most clearly defined role for these class Upeptide complexes is to cause