✦ LIBER ✦

Allele loss in colorectal cancer at the Cowden disease/Juvenile Polyposis locus on 10q

✍ Scribed by Ian M. Frayling; Walter F. Bodmer; Ian P.M. Tomlinson

Book ID: 114136267
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 574 KB
Volume: 97
Category: Article
ISSN: 0165-4608
DOI: 10.1016/s0165-4608(97)00011-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Sporadic breast cancers exhibit loss of

Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locus

✍ Baljit Singh; Michael M. Ittmann; John J. Krolewski 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 1 views

Cowden disease, a dominantly inherited syndrome characterized by a variety of proliferative lesions and predisposition to breast and thyroid cancer, has recently been linked to the polymorphic marker D10S215 on chromosome segment 10q23. Loss of heterozygosity in prostate cancer is linked to the same

Allelic imbalance, including deletion of

Allelic imbalance, including deletion of PTEN/MMAC1, at the Cowden disease locus on 10q22-23, in hamartomas from patients with cowden syndrome and germline PTEN mutation

✍ Debbie J. Marsh; Patricia L. M. Dahia; Valérie Coulon; Zimu Zheng; Françoise Dor 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 174 KB 👁 3 views

Cowden disease (CD) is a rare, autosomal dominant inherited cancer syndrome characterized by multiple benign and malignant lesions in a wide spectrum of tissues. While individuals with CD have an increased risk of breast and thyroid neoplasms, the primary features of CD are hamartomas. The gene for

Frequent allelic loss at the TOC locus o

Frequent allelic loss at the TOC locus on 17q25.1 in primary breast cancers

✍ Koichi Fukino; Aritoshi Iida; Akira Teramoto; Goi Sakamoto; Fujio Kasumi; Yusuke 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 99 KB 👁 1 views

Sporadic breast cancers often show allelic losses on the long arm of chromosome 17. Since the BRCA1 gene lies at 17q21.1 and the TOC locus, associated with esophageal cancer, lies at 17q25.1, either gene could be the target of those losses. We examined both loci in 178 primary breast cancers, using