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All-trans retinoic acid-induced vasculitis and hemonecrosis of the ileum in a patient with acute promyelocytic leukemia

✍ Scribed by Yamada, K; Sugimoto, K; Matsumotot, T; Narumi, K; Oshimi, K

Book ID: 110054172
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 91 KB
Volume: 13
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2401379

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## Abstract ## Background Due to severe side effects in virtually all children treated with a standard dose of 45 mg/m^2^/day all‐__trans__‐retinoic acid (ATRA) for acute promyelocytic leukemia (APL) the AML‐BFM study group reduced the dosage to 25 mg/m^2^/day. For the lack of data on the use of A