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All-Trans Retinoic Acid (ATRA) Desensitization

โœ Scribed by Kearney, D.M.; Ledford, D.K.; Lockey, R.F.


Book ID
119277432
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
190 KB
Volume
117
Category
Article
ISSN
1097-6825

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This study was conducted to compare the results of treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid alone (ATRA) or a combination therapy of ATRA followed by chemotherapy. Forty-three patients treated between February 1992 and February 1996 were included in this study. Ei

ALL-TRANS RETINOIC ACID (ATRA) IN THE TR
โœ C. S. CHIM; Y. L. KWONG; R. LIANG; Y. C. CHU; C. H. CHAN; L. C. CHAN; K. F. WONG ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 498 KB ๐Ÿ‘ 2 views

Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,