All-Trans Retinoic Acid (ATRA) Desensitization
โ Scribed by Kearney, D.M.; Ledford, D.K.; Lockey, R.F.
- Book ID
- 119277432
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 190 KB
- Volume
- 117
- Category
- Article
- ISSN
- 1097-6825
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๐ SIMILAR VOLUMES
This study was conducted to compare the results of treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid alone (ATRA) or a combination therapy of ATRA followed by chemotherapy. Forty-three patients treated between February 1992 and February 1996 were included in this study. Ei
Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,