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‘All-or-none’ mechanism of the molten globule unfolding

✍ Scribed by V.N. Uversky; G.V. Semisotnov; R.H. Pain; O.B. Ptitsyn

Book ID
115927136
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
428 KB
Volume
314
Category
Article
ISSN
0014-5793

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Dry molten globule intermediates and the
Dry molten globule intermediates and the mechanism of protein unfolding
✍ Robert L. Baldwin; Carl Frieden; George D. Rose 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 284 KB

## Abstract New experimental results show that either gain or loss of close packing can be observed as a discrete step in protein folding or unfolding reactions. This finding poses a significant challenge to the conventional two‐state model of protein folding. Results of interest involve dry molten